Universiteit Maastricht

Recent

Rennenberg RJ, Schurgers LJ, Vermeer C, Scholte JB, Houben AJ, de Leeuw PW, Kroon AA. Renal handling of matrix Gla-protein in humans with moderate to severe hypertension. Hypertens Res. 2008 Sep;31(9):1745-51.

Schurgers LJ, Cranenburg EC, Vermeer C. Matrix Gla-protein: the calcification inhibitor in need of vitamin K. Thromb Haemost. 2008 Oct;100(4):593-603.

Shroff RC, McNair R, Figg N, Skepper JN, Schurgers LJ, Gupta A, Hiorns M, Donald AE, Deanfield J, Rees L, Shanahan CM. Dialysis accelerates medial vascular calcification in part by triggering smooth
muscle cell apoptosis. Circulation. 2008 Oct 21;118(17):1748-57.

Li Q, Grange DK, Armstrong NL, Whelan AJ, Hurley MY, Rishavy MA, Hallgren KW, Berkner KL, Schurgers LJ, Jiang Q, Uitto J. Mutations in the GGCX and ABCC6 Genes in a Family with Pseudoxanthoma
Elasticum-Like Phenotypes. J Invest Dermatol. 2008 Sep 18.

Schlieper G, Krüger T, Djuric Z, Damjanovic T, Markovic N, Schurgers LJ, Brandenburg VM, Westenfeld R, Dimkovic S, Ketteler M, Grootendorst DC, Dekker FW, Floege J, Dimkovic N. Vascular access calcification predicts mortality in hemodialysis patients. Kidney Int. 2008 Dec;74(12):1582-7.

Vanschoonbeek K, Wouters K, van der Meijden PE, van Gorp PJ, Feijge MA, Herfs M, Schurgers LJ, Hofker MH, de Maat MP, Heemskerk JW. Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice. Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2023-9. Epub 2008 Aug 28.

van Summeren MJ, Vermeer C, Engelbert RH, Schurgers LJ, Takken T, Fischer K, Kuis W. Extremes in vitamin K status of bone are related to bone ultrasound properties in children with juvenile idiopathic arthritis. Clin Exp Rheumatol. 2008 May-Jun;26(3):484-91.

Shroff RC, Shah V, Hiorns MP, Schoppet M, Hofbauer LC, Hawa G, Schurgers LJ, Singhal A, Merryweather I, Brogan P, Shanahan C, Deanfield J, Rees L. The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not Matrix Gla protein, are associated with vascular stiffness and calcification in
children on dialysis. Nephrol Dial Transplant. 2008 Oct;23(10):3263-71.

Cranenburg EC, Vermeer C, Koos R, Boumans ML, Hackeng TM, Bouwman FG, Kwaijtaal M, Brandenburg VM, Ketteler M, Schurgers LJ. The circulating inactive form of matrix Gla Protein (ucMGP) as a biomarker for cardiovascular calcification. J Vasc Res. 2008;45(5):427-36.

van Summeren MJ, Hameleers JM, Schurgers LJ, Hoeks AP, Uiterwaal CS, Krüger T, Vermeer C, Kuis W, Lilien MR. Circulating calcification inhibitors and vascular properties in children after renal transplantation. Pediatr Nephrol. 2008 Jun;23(6):985-93.

van Summeren MJ, van Coeverden SC, Schurgers LJ, Braam LA, Noirt F, Uiterwaal CS, Kuis W, Vermeer C.
Vitamin K status is associated with childhood bone mineral content. Br J Nutr. 2008 Oct;100(4):852-8.

van Summeren MJ, Spliet WG, van Royen-Kerkhof A, Vermeer C, Lilien M, Kuis W, Schurgers LJ. Calcinosis in juvenile dermatomyositis: a possible role for the vitamin K-dependent protein matrix Gla protein. Rheumatology (Oxford). 2008 Mar;47(3):267-71.

Wallin R, Schurgers L, Wajih N. Effects of the blood coagulation vitamin K as an inhibitor of arterial
calcification. Thromb Res. 2008;122(3):411-7.

Van Langendonckt A, Punyadeera C, Kamps R, Dunselman G, Klein-Hitpass L, Schurgers LJ, Squifflet J, Donnez J, Groothuis P. Identification of novel antigens in blood vessels in rectovaginal endometriosis.
Mol Hum Reprod. 2007 Dec;13(12):875-86.

Li Q, Jiang Q, Schurgers LJ, Uitto J. Pseudoxanthoma elasticum: reduced gamma-glutamyl carboxylation of matrix gla protein in a mouse model (Abcc6-/-). Biochem Biophys Res Commun. 2007 Dec 14;364(2):208-13.

Hermans MM, Vermeer C, Kooman JP, Brandenburg V, Ketteler M, Gladziwa U, Rensma PL, Leunissen KM, Schurgers LJ. Undercarboxylated matrix GLA protein levels are decreased in dialysis patients and related to parameters of calcium-phosphate metabolism and aortic augmentation index.
Blood Purif. 2007;25(5-6):395-401.

Schurgers LJ, Spronk HM, Skepper JN, Hackeng TM, Shanahan CM, Vermeer C, Weissberg PL, Proudfoot D. Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification. J Thromb Haemost. 2007 Dec;5(12):2503-11.

Gheduzzi D, Boraldi F, Annovi G, DeVincenzi CP, Schurgers LJ, Vermeer C, Quaglino D, Ronchetti IP.
Matrix Gla protein is involved in elastic fiber calcification in the dermis of pseudoxanthoma elasticum patients. Lab Invest. 2007 Oct;87(10):998-1008.

Golledge J, Jayalath R, Oliver L, Parr A, Schurgers L, Clancy P. Relationship between CT anthropometric measurements, adipokines and abdominal aortic calcification. Atherosclerosis. 2008 Mar;197(1):428-34.

Cario-Toumaniantz C, Boularan C, Schurgers LJ, Heymann MF, Le Cunff M, Léger J, Loirand G, Pacaud P.
Identification of differentially expressed genes in human varicose veins: involvement of matrix gla protein in extracellular matrix remodeling. J Vasc Res. 2007;44(6):444-59.

Cranenburg EC, Schurgers LJ, Vermeer C. Vitamin K: the coagulation vitamin that became omnipotent.
Thromb Haemost. 2007 Jul;98(1):120-5. Review.

Göritz C, Thiebaut R, Tessier LH, Nieweg K, Moehle C, Buard I, Dupont JL, Schurgers LJ, Schmitz G, Frieger FW. Glia-induced neuronal differentiation by transcriptional regulation. Glia. 2007 55: 1108-22.

Knapen MH, Schurgers LJ, Vermeer C. Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007 Jul;18(7):963-72.

Schurgers LJ, Teunissen KJ, Hamulyák K, Knapen MH, Vik H, Vermeer C. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood. 2007 Apr 15;109(8):3279-83.

Schurgers LJ, Spronk HM, Soute BA, Schiffers PM, DeMey JG, Vermeer C. Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats. Blood. 2007 Apr 1;109(7):2823-31.

Stafford DW, Roberts HR, Vermeer C. Vitamin K supplementation during oral anticoagulation: concerns.
Blood. 2007 Apr 15;109(8):3607; author reply 3607-8

Bügel S, Sørensen AD, Hels O, Kristensen M, Vermeer C, Jakobsen J, Flynn A, Mølgaard C, Cashman KD.
Effect of phylloquinone supplementation on biochemical markers of vitamin K status and bone turnover in postmenopausal women. Br J Nutr. 2007 Feb;97(2):373-80

Willems HP, den Heijer M, Gerrits WB, Schurgers LJ, Havekes M, Blom HJ, Bos GM. Oral anticoagulant treatment with coumarin derivatives does not influence plasma homocysteine concentration. Eur J Intern Med. 2006 Mar;17(2):120-4.

Thijssen HH, Vervoort LM, Schurgers LJ, Shearer MJ. Menadione is a metabolite of oral vitamin K.
Br J Nutr. 2006 Feb;95(2):260-6.

Panis B, Vermeer C, van Kroonenburgh MJ, Nieman FH, Menheere PP, Spaapen LJ, Rubio-Gozalbo ME.
Effect of calcium, vitamins K1 and D3 on bone in galactosemia. Bone. 2006 Nov;39(5):1123-9.

J. Janzen, L.J. Schurgers, C. Vermeer, F. Joris, J.-P. Musy, J. Schmidli. Mediakalzifikationen in einem aneurysma des arcus aortae. Perfusion 2006; 19: 237-241.